منابع مشابه
Autoimmune disease and unexplained pulmonary hypertension.
T he article by Barst et all provides new and important information related to the association of unexplained pulmonary hypertension in children with the major histocompatibility complex (MHC) and has opened up a new dimension of investigation. There is good rationale for immune mediation of pulmonary hypertension as detailed in the article, given the presence of this condition in patients with...
متن کاملDetection of Chlamydia pneumoniae in unexplained pulmonary hypertension.
The pathogenesis of primary pulmonary hypertension is still unclear. The case of a 68-yr-old female patient who complained of recurrent dizzy spells and collapses over a period of 6 weeks and died of global cardiac failure is presented. Autopsy revealed severe pulmonary hypertension, slight chronic bronchitis, and bronchiolitis as well as intra-alveolar accumulation of macrophages. Chlamydiae w...
متن کاملUnexplained pulmonary hypertension in peritoneal dialysis and hemodialysis patients.
OBJECTIVES To compare the prevalence of unexplained pulmonary artery hypertension (PAH) in hemodialysis (HD) and peritoneal dialysis (PD) patients and to compare laboratory parameters between patients with unexplained PAH and those with normal pulmonary artery pressure (PAP). METHODS We retrospectively reviewed the medical records of 278 chronic HD and 145 chronic PD patients. Laboratory find...
متن کاملElastase and the pathobiology of unexplained pulmonary hypertension.
Our laboratory has focused on the increased activity of an endogenous vascular elastase in the pathobiology of pulmonary hypertension and on the mechanisms by which it is upregulated and by which it orchestrates abnormal remodeling of the vessel wall, specifically the induction of growth factors, the induction of the glycoprotein tenascin, which amplifies the proliferative response, and fibrone...
متن کاملUnexplained iron deficiency in idiopathic and heritable pulmonary arterial hypertension.
BACKGROUND Anaemia is common in left heart failure and is associated with a poorer outcome. Many patients with pulmonary arterial hypertension (PAH) are anaemic or iron-deficient. This study was performed to investigate the prevalence of iron deficiency in PAH and to identify possible causes. METHODS All patients with idiopathic or heritable PAH diagnosed in 1995-2008 were identified. Control...
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ژورنال
عنوان ژورنال: Circulation
سال: 1982
ISSN: 0009-7322,1524-4539
DOI: 10.1161/01.cir.65.4.651